Why are you using PodFarm standalone? Shut that shit down and just stick the VST version on the track in Reaper. I actually couldn't tell you how to get the output of the standalone version into Reaper to begin with, so if you've actually got that happening, then you know something I don't. My guess, though, is that you don't actually, and that's the problem. I also suspect that your use of the word "feedback" is questionable. I'm thinking you mean it's noisy, cause the only way it's going to feedback is if you've got it coming out the speakers really loud. So, shut down the standalone thing. Go into reaper and select the UX1's ASIO drivers as your audio device. Stick the PodFarm VST on your guitar track. Remember that if all you want is a guitar amp sim, then you don't have to use the whole bloated PodFarm plug, just use the PodFarm Guitar Amps plugin and save your CPU for other things. If you want some of the "pedals" or other effects from PodFarm, they also can be used as individual plugins. All of the routing/mixing stuff that full PF does is redundant to Reaper's own functionality. I haven't really ever down tests to see how many of the single plugs you have to run at one time before the all-in-one plug would be more efficient, but... Turn off the noise gate. If you need it, then there's an issue with your guitar which should be fixed rather than using an electronic cough medicine to treat the symptom. Usually, the input knob at unity is about right when you're plugged into the Instrument input because Line6 designed the things to play together like that, but that knob is meant to get your input to a reasonable nominal level, and should be set so that you're hitting the "amp" the way you want. If you're looking for crunch, and can't get enough by turning the actual Gain knob on the virtual amp, then turn up the input. If you are shooting for cleanish, but it's still crunchy even with Gain most of the way down, maybe try turning the input down a bit. Course, this all assumes you've chosen an appropriate model to begin with. The Out knob is there to set the level that comes out of PodFarm on its way to the rest of Reaper. Once you've got In and all your amp knobs set, if it's just way too loud on the master meter, then turn that Out knob down. OTOH if it's way too quiet, and you find yourself pushing the track fader way up to get it set in the mix, then turn this knob up.